The research behind every compound we prescribe.

Compound research, answered.

• What is NAD+ and why does it matter as you age?

  NAD+ (nicotinamide adenine dinucleotide) is a coenzyme your cells use to produce energy and repair DNA, and levels naturally decline with age. That decline is one reason NAD+ research has expanded so quickly over the last decade, with human trials studying NMN, nicotinamide riboside, and injectable NAD+ as longevity interventions.

• Why is glutathione given as an injection instead of a pill?

  Oral glutathione has poor bioavailability because it gets broken down in the digestive tract. Injectable glutathione bypasses that breakdown, which is why most clinical research in adults uses intramuscular or intravenous routes for measuring antioxidant and skin biology outcomes.

• What does GHK-Cu actually do for skin?

  GHK-Cu is a copper peptide your body produces naturally, with plasma levels dropping roughly 60 percent between ages 20 and 60. Topical research shows GHK-Cu modulates over 4,000 genes involved in collagen synthesis and dermal remodeling, which is why it's studied for fine lines, skin density, and post-procedure recovery.

• Is niacinamide the same as NAD+?

  Niacinamide is a form of vitamin B3 that your skin cells convert into NAD+ through the salvage pathway. It's the most clinically studied topical precursor for skin NAD+ biology, with strong evidence for barrier function, pigmentation, and photodamage protection.

• How does Yuvia decide which studies to feature?

  We prioritize the most recent peer-reviewed human research from journals like Nature, The Lancet, and Cell Metabolism, alongside the foundational papers that established each compound's mechanism. Every citation lists the study title, authors, journal, and year so you can look it up on PubMed or the publishing journal and verify it yourself.

• Are compounded medications FDA-approved for longevity?

  No. Compounded medications are legal and prepared by licensed pharmacies based on a prescription, but they aren't FDA-approved for off-label longevity use. Yuvia's board-certified specialists prescribe based on a patient evaluation and the published clinical evidence, the same way many longevity-focused specialists have done for years.